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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CASS4
All Species:
10.61
Human Site:
T258
Identified Species:
23.33
UniProt:
Q9NQ75
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NQ75
NP_001157588.1
786
87144
T258
G
K
A
S
V
R
N
T
P
L
T
S
F
A
E
Chimpanzee
Pan troglodytes
XP_001169779
786
87081
T258
G
K
A
S
V
R
N
T
P
L
T
S
F
A
E
Rhesus Macaque
Macaca mulatta
XP_001090515
786
86837
T258
G
K
A
S
V
R
N
T
P
L
P
T
F
A
E
Dog
Lupus familis
XP_534461
746
82524
K240
K
N
V
P
M
Q
K
K
L
S
L
P
E
I
P
Cat
Felis silvestris
Mouse
Mus musculus
Q08EC4
804
88602
N256
L
E
K
A
D
V
R
N
V
S
M
T
S
F
T
Rat
Rattus norvegicus
Q63767
968
104244
L381
G
P
N
G
R
D
P
L
L
D
V
Y
D
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509857
821
90320
S288
K
Q
A
S
P
S
N
S
P
E
K
R
A
P
F
Chicken
Gallus gallus
XP_417499
814
90427
Q280
P
E
K
T
G
L
K
Q
N
S
S
V
H
S
M
Frog
Xenopus laevis
NP_001084484
853
95724
K269
V
P
M
S
P
E
K
K
D
I
K
T
C
R
K
Zebra Danio
Brachydanio rerio
XP_001341038
774
86396
P265
I
L
P
A
R
I
W
P
E
K
K
H
C
P
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782316
831
91548
L255
K
S
P
S
M
S
T
L
S
M
S
T
L
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
93.6
64.2
N.A.
61
22.3
N.A.
51.4
43.4
38.5
29
N.A.
N.A.
N.A.
N.A.
23.8
Protein Similarity:
100
98.8
96
72.3
N.A.
71.5
38
N.A.
66.8
60.5
55.6
45.2
N.A.
N.A.
N.A.
N.A.
39.7
P-Site Identity:
100
100
86.6
0
N.A.
0
6.6
N.A.
26.6
0
6.6
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
93.3
13.3
N.A.
20
6.6
N.A.
40
26.6
26.6
6.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
37
19
0
0
0
0
0
0
0
0
10
28
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
19
0
0
% C
% Asp:
0
0
0
0
10
10
0
0
10
10
0
0
10
10
0
% D
% Glu:
0
19
0
0
0
10
0
0
10
10
0
0
10
0
28
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
28
10
10
% F
% Gly:
37
0
0
10
10
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% H
% Ile:
10
0
0
0
0
10
0
0
0
10
0
0
0
10
10
% I
% Lys:
28
28
19
0
0
0
28
19
0
10
28
0
0
0
10
% K
% Leu:
10
10
0
0
0
10
0
19
19
28
10
0
10
0
0
% L
% Met:
0
0
10
0
19
0
0
0
0
10
10
0
0
0
10
% M
% Asn:
0
10
10
0
0
0
37
10
10
0
0
0
0
0
0
% N
% Pro:
10
19
19
10
19
0
10
10
37
0
10
10
0
19
19
% P
% Gln:
0
10
0
0
0
10
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
19
28
10
0
0
0
0
10
0
10
0
% R
% Ser:
0
10
0
55
0
19
0
10
10
28
19
19
10
10
10
% S
% Thr:
0
0
0
10
0
0
10
28
0
0
19
37
0
0
10
% T
% Val:
10
0
10
0
28
10
0
0
10
0
10
10
0
10
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _